For almost a half of a century estrogen has been the flagship for, and the cornerstone of, the modern medical approach to Hormone Replacement Therapy (HRT). Leading this cause has been the pharmaceutical synthetic estrogen, made from horse urine, called premarin.
Unfortunately the history of premarin HRT is laden with clinical research highlighting the horrors of unopposed estrogen therapy and its carcinogenic relationship. Later efforts to balance these known side effects saw marginal improvements when a synthetic progesterone was added.
Obviously, the increased risk of cancers stood in stark contrast to the miracles and wondrous promises of soft feminine bodies, improved muscle tone of the breasts, enhanced sex drive, improved menstrual cycles and the reduced dread of menopause.
The first recognized disadvantages that manifested were unwanted weight gain, exacerbated PMS types symptoms, uterine bleeding, fluid retention induced bloating with the associated irritability and headaches.
The famous Harvard Medical School conducted the Nurses’ Health Study that was published in the New England Journal of Medicine. Started in 1976 and expanded in 1989, the information provided by the 238,000 dedicated nurse-participants has led to many new insights on health and disease. While the prevention of cancer was still the primary focus, the study also produced landmark data on cardiovascular disease, diabetes and many other conditions. These studies, most notably, have shown that diet, physical activity and other lifestyle factors* can powerfully promote better health.
Regardless of all the serendipity, the study concluded that women on estrogen had an increased risk of breast cancer of thirty-two percent to forty-six percent based on data findings.
Cancer has always been at the fore of the consequences of HRT. The Nurses’ Study went on to identify that women taking estrogen and a synthetic progesterone (progestin) actually developed an even higher rate of cancer than those taking just the estrogen.
Additional support for such research is found in the AMERICAN JOURNAL of EPIDEMIOLOGY. Published research demonstrated that long-term estrogen therapy also increased the risk of fatal ovarian cancer. In the seven-year study of over 240,000 pre and postmenopausal women, women taking estrogen for 11 years or more had a 70% higher risk for developing the fatal ovarian cancer.
The trend setter now is a combination of the three estrogens. Estriol is a weak estrogen able to provide the anti-aging benefits with a claimed NO RISK of cancer according to the Medical College of Georgia Study. For women, natural estriol is converted in the liver from the two potent killer estrogens of Estradiol and Estrone.
The University of Nebraska Medical Center has also been testing estriol as a preventative for human breast cancer. They found women with breast cancer have much lower levels of estriol relative to estradiol and estrone than women without breast cancer.
With all of this science the compounding begins. The theory behind the concept on the surface seems reasonable enough. The resultant formulation is straight forward: 80% estriol, and 10% each of estradiol and estrone.
The application: If you use it, it is advocated that you will get the benefits from three different estrogens in a ratio similar to that which your body produces. The bulk of tri-estrogen is estriol, which is the weakest form of estrogen produced on our bodies — and, as mentioned, not only is it the least likely to cause breast cancer, some studies have shown that it actually helps prevent it. So by taking all three estrogens — very small doses of the stronger ones and a higher one of the weakest one, you can eliminate menopausal symptoms, fight osteoporosis and heart disease and help prevent the increased risk of breast cancer.
CAUTION: It’s a great theory and some science, and one that bears watching. The only problem: As with other newer forms of estrogen, there haven’t been any long-term studies done on this.
As with men, women also suffer from decreased hormone production…what an awful thought! Beginning at about 30, women must deal with the decline of their progesterone production. Once the transition through menopause, production of progesterone is virtually nonexistent!
The consequences of such decline manifest in several ways. The visually recognized reduced height, stooped and humpbacked of our aging population. As researchers have repeatedly documented, with the estrogen buildup of the uterine lining – up to one-third of the women employing estrogens were developing uterine cancer.
As a pharmaceutical knee-jerk reaction to the unfolding dilemma of the first generation hormone replacement therapy of the 1970’s, synthetic progesterone suddenly appeared with all of its vast side effects. The Physician’s Desk Reference [PDR] acknowledges that Provera (and other progestins) have adverse reactions such as bloating, headaches, moodiness, birth defects, blood clots in the lungs and/or brain, and even breast cancer.
With the medical flash and flurry to develop estrogen as the Golden-Child of HRT, progesterone had been sadly ignored.
However, our medical history demonstrates that advancing hormone research pushed for vindication with the balancing of the hormones in our body. The Lancet, March 1997 clearly indicated that estrogen does not rebuild the bone matrix, BUT, surprisingly enough progesterone did!
Why science would ignore basic biochemistry is beyond most peoples comprehension. However, Biology 101 would clarify that there is a process to maintaining the calcium structure of the bone matrix. Simply stated, estrogen triggers the removal of bone calcium, the body then recycles it, and the progesterone then directs the mineral back into the bone matrix.
Granted, there is much more to this process. Suffice to say, our estrogen hormone signals specific biological activity to remove calcium from the bone matrix, the body recycles the calcium and the progesterone signals a biological process to reintroduce the revitalized calcium back into our bone matrix.
One can quickly see how increasing ones estrogen in excess of a balance with progesterone could possibly contribute to the rampant epidemic of osteoporosis and countless other health issues. With America suffering under the current weight of estrogen dominance, the potential health risks should be obvious.
The problem was very clearly – too much estrogen and the consequence of trying to balance with a synthetic progesterone!
The real answer to this dilemma appeared in a report about a major clinical trial that compared natural progesterone with the synthetic counterpart, progestin. This was published in 1995 in The Journal of the American Medical Association, (JAMA).
The bottom line, the natural progesterone demonstrated a superior advantage in protecting the heart, elevating the desirable HDL levels and even adding a protection against the dreaded uterine cancer. Additionally, the natural bone building effects were notable and was the lack of the undesirable elements like bloating, moodiness and even the more negative elements associated with the synthetic progesterone.
The beneficial aspects of natural progesterone are always to be considered when balanced with all required hormones. Remember that a women needs a ‘balance’ for the ‘feel-good’ effectiveness and the anti-aging benefits.
Here are some of the beneficial effects of balancing your body with a natural progesterone*.
Improvements in your health are actually easy to achieve. Acquiring our balanced Natural Progesterone Crème is as easy as ordering it. However, you must not ignore the necessary changes that will be required to your diet and lifestyle. These factors, coupled with changing the way you internalize stress and adding an all natural product will offer you great future results.
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